Week 4 was a bit topsy turvy with upsets and blowouts, and Rex Brewer bragging throughout the offices that he won the week…though he did tie with Dane Fuelling. Dave Nathan still leads in the overall standings. How did they pick this week’s games? Check them out below, and if you have yet to do so, make your picks by clicking here, and get them in before 7pm.
 Dave Nathan LW: 36-9 Overall: 124-27 |  Dane Fuelling LW: 37-8 Overall: 115-36 |  Rex Brewer LW: 37-8 Overall: 107-44 | |
| Bluffton at Jay County | Bluffton | Bluffton | Bluffton |
| Blackhawk at South Adams | South Adams | South Adams | South Adams |
| Heritage at Adams Central | Adams Central | Adams Central | Adams Central |
| Woodlan at Southern Wells | Woodlan | Woodlan | Woodlan |
| DeKalb at Columbia City | Columbia City | Columbia City | Columbia City |
| Huntington North at Bellmont | Huntington North | Huntington North | Huntington North |
| Leo at East Noble | East Noble | East Noble | East Noble |
| Norwell at New Haven | Norwell | Norwell | New Haven |
| Carroll at Snider | Carroll | Carroll | Carroll |
| FW North at Luers | FW North | Luers | Luers |
| Northrop at Concordia | Northrop | Northrop | Northrop |
| FW South at Wayne | FW South | Wayne | Wayne |
| Homestead at Dwenger | Dwenger | Dwenger | Homestead |
| Iowa at Rutgers | Iowa | Iowa | Rutgers |
| Oregon State at Oregon | Oregon | Oregon | Oregon |
| Illinois at Indiana | Indiana | Illinois | Indiana |
| Maryland at Wisconsin | Wisconsin | Wisconsin | Wisconsin |
| Purdue at Notre Dame | Notre Dame | Notre Dame | Notre Dame |
| Michigan at Nebraska | Michigan | Michigan | Michigan |
| Washington at Washington State | Washington | Washington | Washington |
| Michigan State at USC | USC | USC | USC |
| Ball State at Connecticut | UConn | UConn | UConn |
| Green Bay at Cleveland | Green Bay | Green Bay | Green Bay |
| Indianapolis at Tennessee | Indianapolis | Indianapolis | Indianapolis |
| Cincinnati at Minnesota | Minnesota | Minnesota | Minnesota |
| Pittsburgh at New England | Pittsburgh | Pittsburgh | Pittsburgh |
| LA Rams at Philadelphia | Philadelphia | Philadelphia | Philadelphia |
| NY Jets at Tampa Bay | Tampa Bay | Tampa Bay | Tampa Bay |
| Las Vegas at Washington | Washington | Washington | Washington |
| Atlanta at Carolina | Atlanta | Atlanta | Atlanta |
| Houston at Jacksonville | Jacksonville | Jacksonville | Jacksonville |
| Denver at LA Chargers | LA Chargers | LA Chargers | Denver |
| New Orleans at Seattle | Seattle | Seattle | Seattle |
| Dallas at Chicago | Dallas | Chicago | Chicago |
| Arizona at San Francisco | San Francisco | San Francisco | San Francisco |
| Kansas City at NY Giants | Kansas City | Kansas City | Kansas City |
| Detroit at Baltimore | Baltimore | Baltimore | Baltimore |
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